In the adult rat brain, the disconnection of entorhinal cortex and hippocampus results in the elevation of PSA in the outer molecular layer of the dentate gyrus. with this increased expression remains for at least 60 days after lesion. 成年大鼠脑内,切断内嗅皮层与海马的神经联系,发现齿回外分子层PSA含量显著增加,并至少可持续60天。